Hippocampal neurogenesis in the subgranular zone SGZ of dentate gyrus DG occurs throughout life and is regulated by pathological and physiological processes. The role of oxidative stress in hippocampal neurogenesis and its response to exercise or neurodegenerative diseases remains controversial. The present study was designed to investigate the impact of oxidative stress, treadmill exercise and sex on hippocampal neurogenesis in a murine model of heightened oxidative stress G93A mice. Immunohistochemistry was used to detect bromodeoxyuridine BrdU labeled proliferating cells, surviving cells, and their phenotype, as well as for determination of oxidative stress 3-NT; 8-OHdG. We conclude that G93A mice show higher hippocampal neurogenesis, in association with higher BDNF expression, yet running did not further enhance these phenomena in G93A mice, probably due to a 'ceiling effect' of an already heightened basal levels of hippocampal neurogenesis and BDNF expression.
Is sex better exercise than walking? - NHS
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Back to Lifestyle and exercise. In fact, no-one has accurately measured how many calories are expended during sex. The current research attempted to fill this research void by recruiting 21 young couples whose energy expenditure during sex was measured and compared with 30 minutes of moderate intensity on a treadmill. So did sex match the treadmill in terms of energy expenditure? The short answer is no, at least not in this small and strictly defined group.